Red. Swollen. Hot. Painful. Signs of inflammation that no
Largo back pain patient desires. Hollstrom & Associates Inc
delivers chiropractic services to decrease back pain
by identifying and addressing any related
inflammation.
INFLAMMATION AND BACK PAIN RELATED
How can you tell if there’s
inflammation? Like other issues, researchers look
for a means to measure it. To measure inflammation, researchers try
to find inflammatory biomarkers, biological markers like tumor
necrosis factor alpha (TNF-α), C-reactive protein (CRP), and interleukin-6,
interleukin-1β, that exposed an increase. Researchers
have discovered that chronic inflammation increased
cytokine production and stimulated pro-inflammatory
pathways that may cause non-specific low back pain. (1)
Researchers observed systemic inflammation in chronic LBP and
may influence transition from acute to persistent low back pain. Specifically,
CRP was found elevated in acute low back pain patients versus control patients. TNF was greater in back pain
patients especially in patients with depression. (2) Since
researchers have already documented that inflammation
is linked to back pain, Hollstrom & Associates Inc knows that
inflammation must be reduced in order to
help reduce Largo back pain.
HOW TO STOP INFLAMMATION
Well, first, know what inflammation does. Researchers
made use of lipopolysaccharide (LPS) to simulate
intervertebral disc degeneration in experiments. They want
to figure out what might potentially decrease
the produced back pain that accompanies it
and/or even avert the degeneration in the first place
so we humans do not have to suffer
low back pain at all! That is a tall order
though, Hollstrom & Associates Inc knows. But follow
this: researchers utilized LPS to establish the
degeneration that preceded low back pain. They found
that procyanidin B3 (PRO-B3) found in our diets prevented
the production of inflammatory markers - tumor necrosis factor α (TNF-Α),
interleukin-6 (IL-6), prostaglandin E2 (PGE2) and nitric oxide – associated
with disc degeneration. It also prevented the loss of the
disc’s gelatinous nucleus pulposus cells and structural damage of
its anulus fibrosus (outer rings of disc). What does all this mean
to researchers seeking a way to stop degenerative
disc degeneration (DDD)? PRO-B3 may be considered as a
treatment agent for intervertebral disc degeneration (IVDD). This is a welcome note for those 80% of us adults who are on track
to have IVDD, a major cause of low back pain. (3) Another recent
paper described that the p38 MAPK inflammatory pathway may be a
way to defer DDD utilizing the tyrosine
kinase inhibitor, Genistein. (4) That’s encouraging for the treatment of Largo back pain and inflammation.
Vitamin D FOR INFLAMMATION
Research states that vitamin D deficiency is linked
with low back pain that is stronger in younger women and in those with more
severe deficiency. (5) Vitamin D deficiency is linked to lumbar
disc disease and more severe low back pain in postmenopausal women. (6) Let’s talk about your vitamin D intake at your next
Largo chiropractic appointment.
CONTACT Hollstrom & Associates Inc
Listen to this PODCAST with Dr. Sarah Murrow on The Back Doctors Podcast with Dr. Michael Johnson. In this episode, Dr. Murrow and her patient present how the Cox® Technic System alleviated back pain due to disc bulges.